Come to TB Journal Club in June and July

Join us in June at Medecins Sans Frontieres and in July at The Crick!

North London TB Journal Club has two very exciting upcoming meetings with eminent hosts and superb venues:

June 2017 hosted by Medecins Sans Frontieres

Date – Tuesday 27th June, 2017

Time – 16.30 -17.30, refreshments served after

Where – LG floor, 10 Furnival St, Chancery Lane, London, EC4A 1AB (map here)

Chair – Bern-Thomas Nyang’wa

Presenter – Catherine Berry

Theme – Treating MDR-TB – DOT, SAT and everything in between

Papers –

(Main paper) Yin et al. Association between Directly Observed Therapy and treatment outcomes in multi drug-resistant tuberculosis: A systematic review and meta-analysis PLoS One. 2016 Mar 1;11(3) (available here)

(Additional paper) Mohr et al. DOT or SAT for Rifampicin-resistant tuberculosis? A non-randomized comparison in a high HIV-prevalence setting PLoS One. 2017 May 18;12(5) (available here)

 

July 2017 hosted by The Francis Crick Institute

Date – Wednesday 5th July, 2017

Time – 14.00 -15.00, please arrive at reception at 13:45 to clear security

Where – The Francis Crick Institute, 1 Midland Road, London, NW1 1AT (map here)

Chair – Robert Wilkinson

Presenter – Angharad Davis

Theme – TB Meningitis

Papers – Heemskerk et al. Intensified Antituberculosis Therapy in Adults with Tuberculous Meningitis. N Engl J Med. 2016 Jan 14;374(2):124-34. (available here)

** PLEASE REGISTER FOR THE CRICK MEET AT EVENTBRITE (FOR FREE) BY FRIDAY 30TH JUNE TO BE ABLE TO CLEAR SECURITY ON THE DAY** (click here)

 

 

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Come to February’s TB Journal Club

Paper: Shen et al. Recurrent tuberculosis in an urban area in China: Relapse or exogenous reinfection? Tuberculosis 2017; 103: 97-104 [available here].

Presenter: Lara Gosce, Institute for Global Health, UCL

Chair: Tom Yates, Institute for Global Health, UCL

Time: 1-2pm, Friday 24 February 2017

Venue: Room 2.18, Chadwick Building, UCL [map here]

 

Please join us this month to discuss a paper on TB recurrence in Shanghai, focusing on the relative contributions made by relapse versus exogenous reinfection. How do we tease these apart? Should China prioritise efforts to improve treatment adherence or to interrupt transmission? All welcome.

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January’s TB Journal Club

Time: 4-5pm on Wednesday 25 January 2017

Venue: Room 2.18, Chadwick Building, University College London [map here]

Speaker: Giovanni Satta

Chair: Tim McHugh

Papers:

Casali N, Broda A, Harris SR, Parkhill J, Brown T, Drobniewski F. Whole Genome Sequence Analysis of a Large Isoniazid-Resistant Tuberculosis Outbreak in London: A Retrospective Observational Study. PLoS Med 2016; 13(10): e1002137. [available here]

Satta G, Witney AA, Shorten RJ, Karlikowska M, Lipman M, McHugh TD. Genetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance. BMC Med 2016; 14(1): 117. [available here]

Happy New Year! This month, North London TB Journal Club will discuss two recent papers on the London isoniazid resistant TB outbreak. We look forward to seeing you there – all welcome.

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Come to November’s TB Journal Club at QMUL

Presenter: Julie Demaret

Chair: Adrian Martineau

Time: 4-5pm, Thursday 24 November 2016

Venue: Room 1.32, Garrod Building, Turner Street, E1 2AD [map here]

Paper: Malherbe et al. Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure. Nat Med 2016; 22(10): 1094-1100. [available here]

Please join us to discuss an interesting paper exploring radiological and molecular correlates of TB cure. What does cure mean? Are all bacilli killed? How might the way we define treatment response influence the way we test new drugs and regimens against Mycobacterium tuberculosis?

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Come to October’s TB Journal Club

This month, we will be discussing a paper that attempts to estimate the number of TB cases being managed in the private sector in India.

Paper: Arinaminpathy et al. The number of privately treated tuberculosis cases in India: an estimation from drug sales data. Lancet Infectious Disease, 2016: published online ahead of print.

Presented by Marc Lipman

Time: 4-5pm, Thursday 13 October 2016

Venue: Tutorial Room 1, lower ground floor, Royal Free Campus, UCL Medical School

All welcome. A map of the campus is available here. Instructions about how to get to the Royal Free are available here. The paper is available here and the supplemental materials are available here.

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TB Journal Club returns in September

Please join us for our first meeting of the 2016/17 academic year, which will be hosted by the MRC Clinical Trials Unit.

Speaker – Riya Moodley

Chair – Patrick Phillips

Time – 12.30 til 13.30 on Tuesday 27 September

Venue – Aviation House

At the meeting, we will be discussing the 2016 update to the WHO treatment guidelines for drug-resistant tuberculosis. You can access the relevant documents here…

the guidelines

the factsheet

frequently asked questions

Were the right drugs promoted and demoted? Was the WHO correct to conditionally recommend use of shorter Bangladesh-style regimens in certain circumstances? How should children be treated? What is the role for surgery in managing drug-resistant TB?

If you plan to attend, please email patrick.phillips@ucl.ac.uk before the meeting. Please plan to arrive 5-10 minutes early to allow time to clear security.

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TB journal club is on summer break

North London TB Journal Club is on a summer break during July and August. However, we will be back in September 2016 under new management – more details soon. In the meantime, you may like to catch up with videos of previous TB events held in North London – the M.tb Transmission Meeting, the World TB Day 2016 event, or the recent RSTMH meeting on the End TB Strategy.

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